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Anti-Mov10 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Mov10 rabbit polyclonal antibody |
Gene Name: | Putative helicase MOV-10 |
Synonyms: | fSAP113, gb110, KIAA1631, MOV10, Putative helicase MOV 10 |
Immunogen: | Recombinant protein corresponding to Mouse Mov10 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 114 kDa |
Observed MW. | 114 kDa |
Uniprot ID: | P23249 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 300-1: 1000 | testis |
Background
Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2. Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7.
Images
 | Western blot analysis of MOV10 (GB113938) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
