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Anti-NAP1L1 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Nucleosome assembly protein 1-like 1 |
Synonyms: | hNRP, NAP 1 related protein, NAP1, NAP1L, NAP1L1, NRP |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NAP1L1 |
Uniprot ID: | P28656 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 45 kDa / 52/55 kDa |
Product Usage Information
WB | Human, Mouse | 1: 1000-1: 2000 | kidney |
Background
Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly. Participates also in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair. Stimulates also homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair. Plays a key role in the regulation of embryonic neurogenesis . Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development . Regulates neurogenesis via the modulation of RASSF10; regulates RASSF10 expression by promoting SETD1A-mediated H3K4 methylation at the RASSF10 promoter .
Images
| Western blot analysis of NAP1L1 (GB114774) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
