Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Napsin-A |
Synonyms: | Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human NAPSIN-A |
Uniprot ID: | O96009 |
Isotype: | IgG1 |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 45 kDa / 35-50 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | K562, HepG2, lung |
Background
Napsin A is an aspartic proteinase that is expressed in normal lung and kidney. In the lung, napsin A is expressed by type II pneumocytes and alveolar macrophages, where it plays a role in processing surfactant protein B. Napsin A is expressed in lung adenocarcinomas, where it can be used to identify primary and metastatic lesions with greater sensitivity compared to TTF-1. Napsin A expression has also been described in other types of cancer, such as kidney and thyroid cancer.
Images
WB analysis of NAPSIN A(GB151010). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |