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Recombinant Anti-NAPSIN A Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Napsin-A |
Synonyms: | Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02 |
Immunogen: | Recombinant protein corresponding to Human NAPSIN-A |
Uniprot ID: | O96009 |
Isotype: | IgG1 |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. / Observed MW. | 45 kDa / 35-50 kDa |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | lung |
Background
Napsin A is an aspartic proteinase that is expressed in normal lung and kidney. In the lung, napsin A is expressed by type II pneumocytes and alveolar macrophages, where it plays a role in processing surfactant protein B. Napsin A is expressed in lung adenocarcinomas, where it can be used to identify primary and metastatic lesions with greater sensitivity compared to TTF-1. Napsin A expression has also been described in other types of cancer, such as kidney and thyroid cancer.
Images
| IHC analysis of NAPSIN A(GB151011). |
| IHC analysis of NAPSIN A(GB151011). |
| IHC analysis of NAPSIN A(GB151011). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
