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| Reactivity: | M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NRG2 rabbit polyclonal antibody |
Gene Name: | Pro-neuregulin-2, membrane-bound isoform |
Synonyms: | Pro-NRG2, Neuregulin-2, NRG-2, Divergent of neuregulin-1, DON-1, Neural- and thymus-derived activator for ERBB kinases, NTAK, NRG2 |
Immunogen: | Recombinant protein corresponding to Human NRG2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Predicted MW. | 92 kDa |
Observed MW. | 95 kDa |
Uniprot ID: | P56974, O35569 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | testis |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | epencephalon, ovary |
Background
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells.
Images
| Western blot analysis of NRG2 (GB112576) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded rat epencephalon using NRG2 (GB112576) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded mouse ovary using NRG2 (GB112576) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded rat ovary using NRG2 (GB112576) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
