Reactivity: | H & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NRP2 rabbit polyclonal antibody |
Gene Name: | Neuropilin-2 |
Synonyms: | Vascular endothelial cell growth factor 165 receptor 2, NRP2, VEGF165R2, NP2, Neuropilin 2 |
Immunogen: | Recombinant protein corresponding to Mouse NRP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane, Secreted |
Predicted MW. | 105 kDa |
Observed MW. | 105 kDa |
Uniprot ID: | O60462 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 300-1: 800 | MCF-7, A549 |
IHC/IF | Human, Mouse, Rat | 1: 650-1: 1300 | colon cancer, kidney |
Background
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Images
Western blot analysis of NRP2 (GB112499) at dilution of 1: 300 | |
Immunofluorescence of paraffin embedded human colon cancer using NRP2 (GB112499) at dilution of 1: 650 (400x lens) | |
Immunofluorescence of paraffin embedded mouse kidney using NRP2 (GB112499) at dilution of 1: 650 (400x lens) | |
Immunofluorescence of paraffin embedded rat kidney using NRP2 (GB112499) at dilution of 1: 650 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |