Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Neurokinin A rabbit polyclonal antibody |
Gene Name: | Protachykinin-1 |
Synonyms: | PPT, Tac1, Nka, Nkna, Tac2, Hs.2563, Neuromedin L, NK2, PPT, Protachykinin 1, Substance K Neuropeptide K, Substance P, tachykinin, precursor 1 |
Immunogen: | Recombinant protein corresponding to Mouse Neurokinin A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P41539, P06767 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain |
Background
Achykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.TAC1 is an abbreviation for protachykinin 1, a protein that is encoded by the TAC1 gene, which is responsible for 4 products of the tachykinin peptide hormone family: substance P, neurokinin A, and the related peptides, neuropeptideK and neuropeptide . Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Images
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Immunohistochemistry of paraffin embedded mouse brain using Neurokinin-A (GB111349) at dilution of 1:1100 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using Neurokinin-A (GB111349) at dilution of 1:1100 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |