Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | mRNA-)-methyltransferase |
Synonyms: | C20orf67, PCIF1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PCIF1 |
Uniprot ID: | P59114 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 81 kDa / 82/72 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver |
Background
Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs . Recruited to the early elongation complex of RNA polymerase II (RNAPII) via interaction with POLR2A and mediates formation of m6A(m) co-transcriptionally.
Images
Western blot analysis of PCIF1 (GB114736) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |