Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PDGF B rabbit polyclonal |
Gene Name: | Platelet-derived growth factor subunit B |
Synonyms: | PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis, platelet derived growth factor subunit B |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PDGFB |
Isotype: | IgG |
Predicted MW. | 27 kDa |
Observed MW. | 27 kDa |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | heart, lung, kidney, brain |
IHC/IF | Mouse, Rat | 1: 200-1: 600 | skin, lung |
Background
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
Images
Western blot analysis of PDGF B (GB11261) at dilution of 1: 1000. Lane 1: Mouse heart tissue lysate Lane 2: Mouse lung tissue lysate Lane 3: Mouse kidney tissue lysate Lane 4: Mouse brain tissue lysate Lane 5: Rat heart tissue lysate Lane 6: Rat lung tissue lysate Lane 7: Rat brain tissue lysate |
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Immunohistochemistry analysis of paraffin embedded rat lung using PDGFB (GB11261) at dilution of 1: 300 | |
Immunohistochemistry analysis of paraffin embedded mouse skin using PDGFB (GB11261) at dilution of 1: 300 | |
Immunohistochemistry analysis of paraffin-embedded mouse pancreas using PDGF B (GB11261) at dilution of 1: 400 |
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Immunohistochemistry analysis of paraffin-embedded rat pancreas using PDGF B (GB11261) at dilution of 1: 400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |