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Anti-PI4K2B Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Phosphatidylinositol 4-kinase type 2-beta |
Synonyms: | PI 4 Kinase type 2 beta, PI4K2B, PI4KII BETA, PI4KIIB, PIK42B |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PI4K2B |
Uniprot ID: | Q8CBQ5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 53 kDa / 54 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1500 | kidney, colon, small intestine |
Background
Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Images
| Western blot analysis of PI4K2B (GB114828) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
