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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PJA2 rabbit polyclonal antibody |
Gene Name: | E3 ubiquitin-protein ligase Praja-2 |
Synonyms: | Praja2, RING finger protein 131, RING-type E3 ubiquitin transferase Praja-2, Pja2, Kiaa0438, Rnf131 |
Immunogen: | Recombinant protein corresponding to Mouse PJA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | Q80U04, Q63364 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 650-1: 1500 | heart |
Background
PJA2, also known as E3 ubiquitin-protein ligase praja-2, RNF131 (ring finger protein 131) or Neurodap1, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms. Significantly conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PJA2 shares 52% identity with PJA1, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation. Encoded by a gene that maps to human chromosome 5q21.
Images
| Immunohistochemistry of paraffin embedded mouse heart using PJA2 (GB112603) at dilution of 1:650 (400x lens) |
| Immunohistochemistry of paraffin embedded rat heart using PJA2 (GB112603) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse heart using PJA2 (GB112603) at dilution of 1:750 (400x lens) |
| Immunofluorescence of paraffin embedded rat heart using PJA2 (GB112603) at dilution of 1:750 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
