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Anti-PPIL2 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PPIL2 rabbit polyclonal |
Gene Name: | RING-type E3 ubiquitin-protein ligase PPIL2 |
Synonyms: | CYC4, Cyclophilin 60, Cyp 60, CYP60, hCyP 60, PPIase, PPIL2, Rotamase PPIL2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PPIL2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
IHC/IF | Mouse | 1: 1800-1: 3600 | pancreas, testis, thymus |
Background
Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse pancreas using PPIL2 (GB113286) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded mouse testis using PPIL2 (GB113286) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded mouse thymus using PPIL2 (GB113286) at dilution of 1: 3600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
