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Anti-PPP2R2D Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PPP2R2D rabbit polyclonal |
Gene Name: | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform |
Synonyms: | MDS026, PP2A subunit B isoform B55-delta, PPP2R2D, Protein phosphatase 2 regulatory subunit B delta, D7Ertd753e, Kiaa1541 |
Immunogen: | Recombinant protein corresponding to Mouse PPP2R2D |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 52 kDa |
Observed MW. | 52 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, testis |
Background
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment .
Images
 | Western blot analysis of PPP2R2D (GB113161) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
