Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PSMD8 rabbit polyclonal |
Gene Name: | 26S proteasome non-ATPase regulatory subunit 8 |
Synonyms: | 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit S14, Psmd8, P31, Nin1p, HYPF, HIP6, Rpn12, S14 |
Immunogen: | Recombinant protein corresponding to Mouse PSMD8 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 40 kDa |
Observed MW. | 30 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, uterine |
IHC | Human, Mouse, Rat | 1: 1300-1: 2600 | colon cancer, liver cancer, placenta, brain, kidney, lung |
Background
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.
Images
Western blot analysis of PSMD8 (GB113140) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded human colon cancer using PSMD8 (GB113140) at dilution of 1: 2600 | |
Immunohistochemistry analysis of paraffin-embedded human liver cancer using PSMD8 (GB113140) at dilution of 1: 2600 | |
Immunohistochemistry analysis of paraffin-embedded human placenta using PSMD8 (GB113140) at dilution of 1: 2600 | |
Immunohistochemistry analysis of paraffin-embedded human brain using PSMD8 (GB113140) at dilution of 1: 2600 | |
Immunohistochemistry analysis of paraffin-embedded mouse brain using PSMD8 (GB113140) at dilution of 1: 2600 | |
Immunohistochemistry analysis of paraffin-embedded mouse kidney using PSMD8 (GB113140) at dilution of 1: 2600 | |
Immunohistochemistry analysis of paraffin-embedded rat kidney using PSMD8 (GB113140) at dilution of 1: 2600 | |
Immunohistochemistry analysis of paraffin-embedded rat lung using PSMD8 (GB113140) at dilution of 1: 2600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |