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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PTMA rabbit polyclonal antibody |
Gene Name: | Prothymosin alpha |
Synonyms: | N-terminally processed, Thymosin alpha, Ptma, Prothymosin alpha like 1 protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PTMA |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P26350, P06302 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | colon, fallopian tubes, lung, lymph node, ovary, spleen |
Background
Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels.
Images
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Immunohistochemistry of paraffin embedded mouse colon using Thymosin (GB111050) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse colon using Thymosin (GB111050) at dilution of 1:750 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse lung using Thymosin (GB111050) at dilution of 1:750 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat colon using Thymosin (GB111050) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat lung using Thymosin (GB111050) at dilution of 1:1500 (400x lens) |
 | Immunofluorescence of paraffin embedded human lymph node using Thymosin (GB111050) at dilution of 1:1500 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse fallopian tubes using Thymosin (GB111050) at dilution of 1:1500 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse lung using Thymosin (GB111050) at dilution of 1:1000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse lymph node using Thymosin (GB111050) at dilution of 1:1000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse ovary using Thymosin (GB111050) at dilution of 1:1000 (400x lens) |
 | Immunofluorescence of paraffin embedded rat colon using Thymosin (GB111050) at dilution of 1:1000 (400x lens) |
 | Immunofluorescence of paraffin embedded rat colon using Thymosin (GB111050) at dilution of 1:1500 (400x lens) |
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Immunofluorescence of paraffin embedded rat spleen using Thymosin (GB111050) at dilution of 1:1500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
