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Anti-PTPMT1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 |
Synonyms: | DUSP23, MOSP, PLIP, PNAS 129, PTEN like phosphatase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PTPMT1 |
Uniprot ID: | Q66GT5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 22 kDa / 25 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | heart, brain |
Background
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity.
Images
| Western blot analysis of PTPMT1 (GB114974) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
