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Anti-Phospho-AMPKα2 (S491) Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | 5'-AMP-activated protein kinase catalytic subunit alpha-2 |
Synonyms: | AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, AMPKA2, AMPKα2, PRKAA, PRKAA2 |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to human AMPK alpha 2 |
Uniprot ID: | P54646 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 62 kDa / 65 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 300-1: 500 | HepG2, MCF7, HT-29 |
Background
PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belongs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity .
Images
 | Western blot analysis of Phospho-AMPK alpha 2(S491) (GB114062) at dilution of 1:300 |
 | Western blot analysis of Phospho-AMPK alpha 2(S491) (GB114062) at dilution of 1:300 The figure above was treated with phospho-blocking pepide, the figure below was treated with non-phospho- blocking pepide |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
