Your shopping cart is empty!
Anti-Phospho-CREB (S133) Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cyclic AMP-responsive element-binding protein 1 |
Synonyms: | CREB-1, CAMP-responsive element-binding protein 1, CAMP responsive element binding protein 1, Active transcription factor CREB, P-CREB |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human CREB（S133） |
Uniprot ID: | P16220 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 37 kDa / 43 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | NIH/3T3, C6 |
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Images
| Western blot analysis of P-CREB (GB114684) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
