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Anti-Phospho-FAK (Y576/Y577) Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Focal adhesion kinase 1 |
Synonyms: | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, protein tyrosine kinase 2, P-FAK |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human FAK（Y576/Y577） |
Uniprot ID: | Q05397 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoskeleton, Membrane, Nucleus |
Predicted MW. / Observed MW. | 119 /114/99 /63/49/120 / 125 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | brain |
Background
FAK is a protein of 125 kD recruited as a participant in focal adhesion dynamics between cells, and has a role in motility and cell survival. FAK is a highly conserved, non-receptor tyrosine kinase originally identified as a substrate for the oncogene protein tyrosine kinase v-src. This cytosolic kinase has been implicated in diverse cellular roles including cell locomotion, mitogen response and cell survival.
Images
| Western blot analysis of (Lambda phosphatase)P-FAK (GB114687) at dilution of 1: 300 The figure above was untreated , the figure bleow was treated with lambda phosphatase. |
| Western blot analysis of P-FAK (GB114687) at dilution of 1: 300 The figure above was treated with phospho-blocking pepide, the figure below was treated with non-phospho- blocking pepide. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
