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Anti-Phospho-GSK3 Beta (S9) Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Glycogen synthase kinase-3 beta |
Synonyms: | GSK3B, Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3, glycogen synthase kinase 3 beta, P-GSK3β |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human GSK3β（Ser9） |
Uniprot ID: | P49841 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 47/48/51 kDa / 46/51 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 600 | HeLa, NIH/3T3, C6 |
Background
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .This antibody recognize the C-terminal of GSK3B.
Images
| Western blot analysis of Phospho-GSK3β(Ser9) (GB114582) at dilution of 1: 300. |
| Western blot analysis of Phospho-GSK3β(Ser9) (GB114582) at dilution of 1: 300. The figure above was treated with phospho-blocking pepide, the figure below was treated with non-phospho- blocking pepide. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
