Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Plxdc2 rabbit polyclonal |
Gene Name: | Plexin domain-containing protein 2 |
Synonyms: | Tumor endothelial marker 7-related protein, Plxdc2, Tem7r, plexin domain containing 2, FLJ14623 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Plxdc2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 60 kDa |
Observed MW. | 60 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 1000-1: 2000 | lung, skin |
Background
PLXDC2 (Plexin-domain containing 2), also named tumor endothelial marker 7-related protein (TEM7R), is a single-pass type I membrane protein with some homology to nidogen and to plexins. PLXDC2 is located in tumor endothelium and plays a role in tumor angiogenesis. Three isoforms of PLXDC2 produced by alternative splicing have been described. Recent finding revealed that PLXDC2 is a mitogen for neural progenitors and functions as a novel regulator of the development of different brain regions, suggesting its role in coordinating proliferation and differentiation in the developing nervous system.
Images
![]() | Western blot analysis of Plxdc2 (GB113508) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |