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Anti-RAB8B Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Ras-related protein Rab-8B |
Synonyms: | RAB8, RAB8B, Ras related protein Rab 8B |
Immunogen: | Recombinant protein corresponding to Mouse RAB8B |
Uniprot ID: | P61028 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 3000 | heart, lung, spleen |
Background
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells.
Images
| Immunohistochemistry analysis of paraffin embedded rat lung using RAB8B (GB114695) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse spleen using RAB8B (GB114695) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded rat heart using RAB8B (GB114695) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded mouse spleen using RAB8B (GB114695) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded mouse lung using RAB8B (GB114695) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
