Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | RACGAP1 rabbit polyclonal antibody |
Gene Name: | Rac GTPase-activating protein 1 |
Synonyms: | CYK4, HsCYK-4, ID-GAP, MgcRacGAP, Racgap1 |
Immunogen: | Recombinant protein corresponding to Mouse Racgap1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm, Cytoplasmic vesicle, Cleavage furrow, Midbody, Cell membrane |
Uniprot ID: | Q9WVM1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 3000 | spleen, testis, thymitis, thymus |
Background
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts.
Images
Immunohistochemistry of paraffin embedded mouse spleen using GAP (GB11308) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse thymitis using GAP (GB11308) at dilution of 1:3000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat spleen using GAP (GB11308) at dilution of 1:1500 (400x lens) | |
Immunohistochemistry of paraffin embedded rat thymus using GAP (GB11308) at dilution of 1:1500 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spleen using GAP (GB11308) at dilution of 1:500 (400x lens) | |
Immunofluorescence of paraffin embedded rat testis using GAP (GB11308) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |