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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RBM3 rabbit polyclonal |
Gene Name: | RNA-binding protein 3 |
Synonyms: | IS1 RNPL, Putative RNA-binding protein 3, RBM3, RNA binding motif protein 3, RNPL |
Immunogen: | Recombinant protein corresponding to Mouse RBM3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 17 kDa |
Observed MW. | 20 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 300-1: 800 | testis |
Background
RBM3, also named as RNPL, is a cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. It reduces the relative abundance of microRNAs, when overexpressed. RBM3 enhances phosphoryaltion of translation initiation factors and active polysome formation. It is up-regulated in human tumors. RBM3 is a potential proto-oncogenic proteins upon overexpression.
Images
 | Western blot analysis of RBM3 (GB113642) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
