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| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RBP4 rabbit polyclonal antibody |
Gene Name: | Retinol-binding protein 4 |
Synonyms: | Plasma retinol-binding protein, PRBP, RBP, Rbp4, RDCCAS |
Immunogen: | Recombinant protein corresponding to Mouse RBP4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. | 23 kDa |
Observed MW. | 23 kDa |
Uniprot ID: | Q00724, 04916 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | plasma |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 1400 | kidney, liver, pancreas |
Background
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
Images
 | Western blot analysis of RBP (GB112481) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse kidney using RBP (GB112481) at dilution of 1: 700 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat kidney using RBP (GB112481) at dilution of 1: 700 (400x lens) |
 | Immunofluorescence of paraffin embedded human liver using RBP (GB112481) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded human pancreas using RBP (GB112481) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using RBP (GB112481) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded rat kidney using RBP (GB112481) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded rat liver using RBP (GB112481) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
