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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Regulator of G-protein signaling 7 |
Synonyms: | RGS7 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RGS7 |
Uniprot ID: | O54829 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 55 kDa / 58 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1500 | brain, cerebellum, hippocampus |
Background
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.
Images
| Western blot analysis of RGS7 (GB114266) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
