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Anti-RHBDD1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Rhomboid-related protein 4 |
Synonyms: | HSD 50, RHBDD1, rhomboid domain containing 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RHBDD1 |
Uniprot ID: | Q8BHC7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 36 kDa / 36 kDa |
Product Usage Information
WB | Human | 1: 800-1: 1500 | K562, Jurkat |
Background
Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.
Images
| Western blot analysis of RHBDD1 (GB115289) at dilution of 1:1000 |
| Western blot analysis of RHBDD1 (GB115289) at dilution of 1:1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
