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Anti-RPL11 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RPL11 rabbit polyclonal antibody |
Gene Name: | 60S ribosomal protein L11 |
Synonyms: | CLL associated antigen KW 12, DBA7, GIG34, ribosomal protein L11, RPL11 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RPL11 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q9CXW4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:1200-1:2400 | liver cancer, liver |
Background
Ribosomal protein L11 is one of 80 mammalian ribosome proteins. It can bind to 5S ribosomal RNA, for it's required for rRNA maturation and formation of the 60S ribosomal subunit. It can inhibit 40S or 60S ribosome biogenesis via mediated p53 induction. Once retained by PICT1 in the nucleolus, RPL11 involve in regulation of the MDM2-P53 pathway and promotion of tumor progression.
Images
| Immunohistochemistry analysis of paraffin embedded human liver cancer using RPL11 (GB114127) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin embedded human liver using RPL11 (GB114127) at dilution of 1: 1200 |
| Immunofluorescence of paraffin embedded human liver using RPL11 (GB114127) at dilution of 1: 1200 |
| Immunofluorescence of paraffin embedded mouse liver using RPL11 (GB114127) at dilution of 1: 1200 |
| Immunofluorescence of paraffin embedded rat liver using RPL11 (GB114127) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
