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Anti-RUNX3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RUNX3 rabbit polyclonal |
Gene Name: | Runt-related transcription factor 3 |
Synonyms: | AML2, CBF alpha 3, CBFA3, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, PEBP2A3, PEBP2aC, RUNX3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3 |
Immunogen: | Recombinant protein corresponding to Mouse RUNX3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44 kDa |
Observed MW. | 44 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver |
Background
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
 | Western blot analysis of RUNX3 (GB113627) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |