Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Roundabout homolog 3 |
Synonyms: | HGPPS, HGPS, RBIG1, RIG1, ROBO3, ROBO3-Specific, Roundabout homolog 3, Roundabout like protein 3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Robo3 |
Uniprot ID: | Q9Z2I4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 150kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1500 | brain, spinal cord |
Background
Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube . In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 . Required for hindbrain axon midline crossing .
Images
Western blot analysis of ROBO3 (GB114674) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |