Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Protein S100-B |
Synonyms: | S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B, S100β |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human S100B |
Uniprot ID: | P04271 |
Isotype: | IgG1 |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm,Secreted |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | Ganglion, brain |
Background
S100B is glial-specific and is expressed primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.
Images
IHC analysis of S100 beta(GB15360). | |
IHC analysis of S100 beta(GB15360). | |
IHC analysis of S100 beta(GB15360). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |