Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SCD1 rabbit polyclonal antibody |
Gene Name: | Acyl-CoA desaturase 1 |
Synonyms: | Acyl-CoA desaturase, Delta(9)-desaturase 1, Delta-9 desaturase 1, FADS5, Fatty acid desaturase 1, SCD, SCD1, SCDOS, Stearoyl-CoA desaturase 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SCD1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 35 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | lung, colon |
Background
SCD (stearoyl-CoA desaturase) is a 37-45 kDa microsomal fatty acid monodesaturase, also commonly known as 9-desaturase, which catalyses the committed step in the biosynthesis of mono-unsaturated fatty acids from saturated fatty acids. The formation of homodimers and oligomers is an intrinsic property of SCD proteins, which may play an important role in regulating the half-life of the SCDenzymes, thus representing a novel regulatory mechanism for SCD enzymes, in addition to the transcriptional and post-translational regulations. A 32-kDa SCD1 degradation product identified may be caused by a major cleavage site at the C-terminus, thus representing a novel degradation product.
Images
Western blot analysis of SCD1 (GB113844) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |