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Anti-SCN4A Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SCN4A rabbit polyclonal antibody |
Gene Name: | Sodium channel protein type 4 subunit alpha |
Synonyms: | HYKPP, HYPP, Nav1.4, SkM1, SCN4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SCN4A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 209 kDa / 180 kDa |
Uniprot ID: | Q9ER60 |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 800 | brain |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 1200 | skeletal muscle |
Background
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders.
Images
| Western blot analysis of SCN4A (GB113903) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded rat skeletal muscle using SCN4A (GB113903) at dilution of 1: 400 |
 | Immunofluorescence analysis of paraffin embedded rat skeletal muscle using SCN4A (GB113903) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
