Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Protein transport protein Sec24A |
Synonyms: | SEC24 related protein A, SEC24A |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SEC24A |
Uniprot ID: | Q3U2P1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 119 kDa / 119-130 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HepG2, 293 |
Background
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
Images
Western blot analysis of SEC24A (GB115328) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |