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| Reactivity: | H & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SIX2 rabbit polyclonal |
Gene Name: | Homeobox protein SIX2 |
Synonyms: | Sine oculis homeobox homolog 2, SIX homeobox 2, SIX2 |
Immunogen: | Recombinant protein corresponding to Mouse SIX2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 33 kDa |
Observed MW. | 37 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 1000 | 239T, HEK293 |
IHC | Mouse, Rat | 1: 1000-1: 2000 | fetal rat |
Background
The SIX proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six members (Six1-Six6) of the Six gene family have been identified in mice and humans. SIX2, containing one homeobox DNA-binding domain, is highly expressed in fetal tissues but expression is limited in adult tissues. SIX2 may be involved in limb tendon and ligament development. It has been previously shown that SIX2 is expressed in developing mesenchymal tissue including head and urogenital system at the time of overt midfacial and renal differentiation. This antibody is a rabbit polyclonal antibody raised against full length SIX2 of human origin.
Images
 | Western blot analysis of SIX2 (GB113136) at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin-embedded mouse fetal rat using SIX2 (GB113136) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded rat fetal rat using SIX2 (GB113136) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
