Reactivity: | H,M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Small conductance calcium-activated potassium channel protein 1 |
Synonyms: | hSK1, KCa2.1, KCNN1, SK, SK1, SKCa 1, SKCA1 |
Immunogen: | Recombinant protein corresponding to Mouse SK1 |
Uniprot ID: | Q9EQR3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Predicted MW. / Observed MW. | 59 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 2000-1: 3000 | brain, kidney, liver |
IHC/IF | Mouse, Rat | 1: 1200-1: 2400 | brain |
Background
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization.
Images
Western blot analysis of KCNN1 (GB115362) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin embedded mouse Brain using KCNN1 (GB115362) at dilution of 1: 1200 | |
Immunohistochemistry analysis of paraffin embedded rat Brain using KCNN1 (GB115362) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |