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Anti-SMARCD1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 |
Synonyms: | BAF60A, BRG1 associated factor 60A, CRACD1, Rsc6p, SMARCD1, SWI/SNF complex 60 kDa subunit |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SMARCD1 |
Uniprot ID: | Q61466 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | liver, brain, testis |
Background
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.
Images
| Immunohistochemistry analysis of paraffin embedded rat liver using SMARCD1 (GB114945) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat brain using SMARCD1 (GB114945) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat testis using SMARCD1 (GB114945) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse testis using SMARCD1 (GB114945) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
