Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SMC3 rabbit polyclonal antibody |
Gene Name: | Structural maintenance of chromosomes protein 3 |
Synonyms: | BAM, Bamacan, BMH, CDLS3, CSPG6, HCAP, SMC 3, SMC protein 3, SMC3, SMC3L1 |
Immunogen: | Recombinant protein corresponding to Mouse SMC3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 142 kDa |
Observed MW. | 142 kDa |
Uniprot ID: | Q9CW03 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, kidney |
Background
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Images
 | Western blot analysis of SMC3 (GB114015) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
