Reactivity: | H,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Small nuclear ribonucleoprotein Sm D1 |
Synonyms: | HsT2456, Sm D autoantigen, Sm D1, SMD1, snRNP core protein D1, SNRPD, SNRPD1 |
Immunogen: | Recombinant protein corresponding to Mouse SNRPD1 |
Uniprot ID: | P62315 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 13 kDa / 13-17 kDa |
Product Usage Information
WB | Human, Rat | 1: 500-1: 800 | heart, kidney, skeletal muscle |
Background
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
Images
Western blot analysis of SNRPD1 (GB114560) at dilution of 1: 50 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |