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Anti-SPRED1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SPRED1 rabbit polyclonal |
Gene Name: | Sprouty-related, EVH1 domain-containing protein 1 |
Synonyms: | Spred-1, hSpred1, NFLS, PPP1R147, Sprouty-related, Suppressor of Ras/MAPK activation, protein phosphatase 1 regulatory subunit 147 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SPRED1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 51 kDa |
Observed MW. | 51kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 300-1: 1000 | brain, lung, placenta |
Background
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).
Images
| Western blot analysis of SPRED1 (GB113773) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
