Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Signal recognition particle 54kDa |
Synonyms: | SRP54 |
Immunogen: | Recombinant protein corresponding to Mouse SRP54 |
Uniprot ID: | P14576 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Product Usage Information
IHC/IF | Rat | 1: 1000-1: 2000 | thyroid gland |
Background
The signal recognition particle (SRP) is a ribonucleoprotein complex that mediates the targeting of proteins to the endoplasmic reticulum (ER). The complex consists of a 7S (or 7SL) RNA and 6 different proteins, and signal recognition particle 54 (SRP54) is one of them. SRP54 binds to the signal sequence of presecretory protein as they emerge from the translating ribosomes, and then transfers them to translocating chain-associating membrane protein (TRAM).
Images
Immunohistochemistry analysis of paraffin embedded rat thyroid gland using SRP54 (GB114144) at dilution of 1: 1000 | |
Immunofluorescence analysis of paraffin embedded rat thyroid gland using SRP54 (GB114144) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |