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Anti-STAM2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | STAM2 rabbit polyclonal |
Gene Name: | Signal transducing adapter molecule 2 |
Synonyms: | STAM-2, Hrs-binding protein, Stam2, Hbp, STAM2A, STAM2B, HSE1 homolog |
Immunogen: | Recombinant protein corresponding to Mouse STAM2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 70 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 1000-1: 2000 | stomach, liver |
Background
Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
Images
 | Western blot analysis of STAM2 (GB113020) at dilution of 1: 2000 Lane 1: Mouse liver tissue lysate Lane 2: Mouse stomach tissue lysate |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
