Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Tricarboxylate transport protein, mitochondrial |
Synonyms: | CIC, Citrate transport protein, CTP, SLC20A3, Tricarboxylate carrier protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Slc25a1 |
Uniprot ID: | Q8JZU2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion inner membrane |
Predicted MW. / Observed MW. | 34 kDa / 30 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | brain |
IHC/IF | Mouse, Rat | 1: 600-1: 1800 | kidney |
Background
Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation.
Images
Western blot analysis of SLC25A1 (GB114975) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded rat kidney using SLC25A1 (GB114975) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin embedded mouse kidney using SLC25A1 (GB114975) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |