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Anti-Tryptophan Hydroxylase/TPH Rabbit pAb (100 μl)
| Reactivity: | M,R & H |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Tryptophan Hydroxylase/TPH rabbit polyclonal |
Gene Name: | Tryptophan 5-hydroxylase 1 |
Synonyms: | Tryptophan 5-monooxygenase 1, Tph1, Tph, L tryptophan hydroxylase, Indoleacetic acid 5 hydroxylase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Tryptophan Hydroxylase |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 51 kDa |
Observed MW. | 51 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | liver |
IHC | Human | 1: 400-1: 800 | liver |
Background
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
Images
| Western blot analysis of TPH (GB112524) at dilution of 1: 2000 Lane 1: Mouse liver tissue lysate Lane 2: Rat liver tissue lysate |
 | Immunohistochemistry analysis of paraffin-embedded human liver using TPH (GB112524) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
