Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TRIM26 rabbit polyclonal |
Gene Name: | Tripartite motif-containing protein 26 |
Synonyms: | Zinc finger protein 173, Trim26, Znf173, RNF95, Acid finger protein, AFP, RING finger protein 95 |
Immunogen: | Recombinant protein corresponding to Mouse TRIM26 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 63 kDa |
Observed MW. | 63 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 1500 | pancreas |
Background
TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation.
Images
Western blot analysis of TRIM26 (GB113035) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |