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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Tumor susceptibility gene 101 protein |
Synonyms: | TSG101(N-terminal), TSG10, VPS23, tumor susceptibility 101 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human TSG101 |
Uniprot ID: | Q61187 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 44 kDa / 46 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 500 | brain, heart, liver |
Background
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation.
Images
| Western blot analysis of tsg101 (GB12618) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
