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Anti-Transferrin Receptor 2/TFR2 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Transferrin Receptor 2/TFR2 rabbit polyclonal |
Gene Name: | Transferrin receptor protein 2 |
Synonyms: | TfR2, Trfr2, HFE3, TFRC2, Transferrin receptor 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Transferrin Receptor 2/TFR2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse | 1: 200-1: 400 | liver |
Background
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Images
| Immunohistochemistry analysis of paraffin-embedded human liver using TFR2 (GB113731) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin-embedded mouse liver using TFR2 (GB113731) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
