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Anti-XPNPEP3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | XPNPEP3 rabbit polyclonal |
Gene Name: | Xaa-Pro aminopeptidase 3 |
Synonyms: | X-Pro aminopeptidase 3, Aminopeptidase P3, APP3, Xpnpep3, APP3c, APP3m |
Immunogen: | Recombinant protein corresponding to Mouse XPNPEP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 50 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain |
Background
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. Also shows low activity towards peptides with Ala or Ser at the P1 position. Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.
Images
 | Western blot analysis of XPNPEP3 (GB113019) at dilution of 1: 1000 Lane 1: HepG2 cell lysate Lane 2: PC-3 cell lysate Lane 3: Mouse brain tissue lysate Lane 4: Rat brain tissue lysate |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
