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Anti-YTHDF1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | YTHDF1 rabbit polyclonal antibody |
Gene Name: | YTH domain-containing family protein 1 |
Synonyms: | Dermatomyositis associated with cancer putative autoantigen 1 homolog, DACA-1 homolog, Ythdf1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse YTHDF1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | P59326 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1000 | brain |
Background
YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation.
Images
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Immunohistochemistry of paraffin embedded mouse brain using YTHDF1 (GB111390) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
