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Anti-ZAP70 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ZAP70 rabbit polyclonal antibody |
Gene Name: | Tyrosine-protein kinase ZAP-70 |
Synonyms: | 70 kDa zeta-chain associated protein, Srk, Syk-related tyrosine kinase, Zap70, Zap-70 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ZAP70 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | A0A0R4J8U1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 650-1: 2000 | lymph node, spleen |
Background
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development.
Images
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Immunohistochemistry of paraffin embedded rat spleen using Zap70 (GB111109) at dilution of 1:650 (400x lens) |
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Immunofluorescence of paraffin embedded mouse spleen using Zap70 (GB111109) at dilution of 1:1300 (400x lens) |
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Immunofluorescence of paraffin embedded rat lymph node using Zap70 (GB111109) at dilution of 1:1300 (400x lens) |
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Immunofluorescence of paraffin embedded rat spleen using Zap70 (GB111109) at dilution of 1:1300 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |